Product Name :
PDIA2 Recombinant Rabbit Monoclonal Antibody [JF97-08]
Predicted band size :
57 kDa
Observed band size :
Synonyms:
Pancreas specific protein disulfide isomerase antibody Pancreas-specific protein disulfide isomerase antibody Pancreatic protein disulfide isomerase antibody PDA2 antibody PDI antibody PDIA2 antibody PDIA2_HUMAN antibody PDIp antibody PDIR antibody Protein disulfide isomerase A2 antibody 展开
Function :
Oxidoreductase-protein disulfide isomerase (PDI) is a homodimer consisting of subunits that catalyzes thiol-disulfide exchange, mediates folding of newly synthesized proteins and functions as a molecular chaperone. PDI localizes to the lumen of the endoplasmic reticulum (ER), where in conjunction with folding-helper proteins, such as immunoglobulin heavy chain binding protein (BiP), mediates tertiary and quaternary protein-processing. Cell surface PDI induces sulfhydryl-mediated conformational changes in integrin-mediated adhesion receptor-ligand interactions, thereby regulating integrin responses and cell adhesion. Additionally, PDI functions as a subunit of two more complex enzyme systems: the prolyl-4-hydroxylase and the triacylglycerol transfer proteins.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human PDIA2 aa 405-450.(2,3-Dihydrobenzofuran-7-yl)boronic acid uses
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, FC
Coupling :
unconjugated
Clone number:
JF97-08
RRID:
AB_3070330
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.4-(Methoxycarbonyl)nicotinic acid site Aliquot store at -20℃ or -80℃.PMID:33583346 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 57 kDa
Positive control :
NIH/3T3 cell lysate, human liver tissue lysate, Hela.