Entricular myocytes in intact RyR2R4496C+/- hearts The markedly

Entricular myocytes in intact RyR2R4496C+/- hearts The markedly altered spatial and temporal profiles of intracellular Ca2+ dynamics in PLN-/-/RyR2-R4496C+/- or PLN-/- ventricular myocytes may possibly have resulted from cellular damage…