Product Name :
SYVN1 Recombinant Rabbit Monoclonal Antibody [JE44-67]
Predicted band size :
68 kDa
Observed band size :
68 kDa
Synonyms:
1200010C09Rik antibody DER3 antibody E3 ubiquitin-protein ligase synoviolin antibody HMG coA reductase degradation 1 homolog antibody HRD1 antibody KIAA1810 antibody MGC40372 antibody OTTHUMP00000230429 antibody OTTHUMP00000230430 antibody OTTHUMP00000230431 antibody 展开
Function :
E3 ubiquitin-protein ligase synoviolin is an enzyme that in humans is encoded by the SYVN1 gene. This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. This gene and the mitochondrial ribosomal protein L49 gene use in their respective 3′ UTRs some of the same genomic sequence.270065-78-6 Chemscene Sequence analysis identified two transcript variants that encode different isoforms.Fmoc-N,N-dimethyl-L-Asparagine custom synthesis
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human SYVN1 aa 150-250.
Species reactivity:
Human
Verify application:
WB, IF-Cell, FC
Coupling :
unconjugated
Clone number:
JE44-67
RRID:
AB_3096818
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.PMID:33750623 Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 68 kDa
Positive control :
HEK-293 cell lysate, HepG2 cell lysate, Raji cell lysate, HCT 116 cell lysate, HeLa cell lysate, HeLa.