Product Name :
Sin3B Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
Histone deacetylase complex subunit Sin3b antibody Paired amphipathic helix protein Sin3b antibody SIN3 homolog B transcription regulator antibody SIN3 transcription regulator family member B antibody SIN3 transcription regulator homolog B antibody SIN3B antibody SIN3B_HUMAN antibody Transcriptional corepressor Sin3b antibody
Function :
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. Contains 3 PAH (paired amphipathic helix) repeats. subunit:Interacts with FOXK1/MNF, MXI, MAD, NCOR1 and SAP30. Interaction with SDS3 enhances the interaction with HDAC1 to form a complex. Interacts with MAD3, MAD4, MAEL, REST and SETDB1 (By similarity). Interacts with HCFC1.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
The antiserum was produced against synthesized peptide derived from human SIN3B. AA range:221-270
Species reactivity:
Human
Verify application:
WB, IF
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Buy2,5-Dihydroxyterephthalic acid Aliquot store at -20℃ or -80℃.3-Penten-2-one web Avoid repeated freeze / thaw cycles.PMID:33455517
Storage buffer solution:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
130 kDa
Positive control :
Brain,Duodenum,Lung,Skin,