Product Name :
RING1 Recombinant Rabbit Monoclonal Antibody [JE34-66]
Predicted band size :
42 kDa
Observed band size :
50 kDa
Synonyms:
Ring1A antibody E3 ubiquitin-protein ligase RING1 antibody Polycomb complex protein RING1 antibody Really interesting new gene 1 protein antibody RING finger protein 1 antibody Ring1 antibody RING1_HUMAN antibody RING1A antibody Rnf1 antibody Transcription repressor Ring1A antibody
Function :
E3 ubiquitin-protein ligase RING1 is an enzyme that in humans is encoded by the RING1 gene. This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain.Geranylgeraniol site The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human RING1 aa 150-250.
Species reactivity:
Human
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
JE34-66
RRID:
AB_3072577
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.887144-97-0 Price Aliquot store at -20℃.PMID:33443967 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 42 kDa
Positive control :
THP-1 cell lysate, Jurkat cell lysate, 22RV1 cell lysate, human prostate tissue.