Product Name :
TRPA1 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
ANKTM 1 antibody ANKTM1 antibody Ankyrin-like with transmembrane domains protein 1 antibody Transformation sensitive protein p120 antibody Transformation-sensitive protein p120 antibody Transient receptor potential cation channel subfamily A member 1 antibody TRPA 1 antibody Trpa1 antibody TRPA1_HUMAN antibody
Function :
Receptor-activated non-selective cation channel involved in detection of pain and possibly also in cold perception and inner ear function. Has a central role in the pain response to endogenous inflammatory mediators and to a diverse array of volatile irritants, such as mustard oil, cinnamaldehyde, garlic and acrolein, an irritant from tears gas and vehicule exhaust fumes. Is also activated by menthol (in vitro). Acts also as a ionotropic cannabinoid receptor by being activated by delta9-tetrahydrocannabinol (THC), the psychoactive component of marijuana. May be a component for the mechanosensitive transduction channel of hair cells in inner ear, thereby participating in the perception of sounds. Probably operated by a phosphatidylinositol second messenger system.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Recombinant protein within Human TRPA1 aa 505-755 / 1,119.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IHC-P
Coupling :
unconjugated
Clone number:
RRID:
AB_3069285
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.606143-93-5 Data Sheet Aliquot store at -20℃.5-Hydroxymethylfurfural site Avoid repeated freeze / thaw cycles.PMID:33551388
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 127 kDa
Positive control :
L929, MG-63, NIH-3T3, rat brain tissue, human skin tissue, human esophagus tissue, mouse colon tissue.