Product Name :
3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-1H-pyrazole (CAS 443919-96-8)
Synonym :
Application :
3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-1H-pyrazole is a dual inhibitor of Cox-2 and 5-LO
CAS:
443919-96-8
Purity:
>95%
Molecular Weight:
536.6
Formula :
C29H29FN2O5S
Physical state:
Solid
solubility :
Soluble in ethanol (~5 mg/ml), DMSO (~30 mg/ml), and DMF (~30 mg/ml). Insoluble in water.
Shipping Condition :
Store at -20° C
Melting point:
~703.86-95-3 chemscene 6° C (Predicted)
SMILES:
COC1(CCOCC1)C2=CC(=CC(=C2)F)OCC3=NN(C(=C3)C4=CC=CC=C4)C5=CC=C(C=C5)S(=O)(=O)C
References:
:Synthesis and activity of a new methoxytetrahydropyran derivative as dual cyclooxygenase-2/5-lipoxygenase inhibitor.268729-12-0 web | Barbey, S.PMID:33471569 , et al. 2002. Bioorg Med Chem Lett. 12: 779-82. PMID: 11859001